Fabrication of an integrated circuit with smaller area, besides reducing the cost of manufacturing, usually causes a reduction in the power dissipation and propagation delay. Using the static CMOS technology to fabricate a circuit that realizes a specific logic function and occupies a minimum space, it must be implemented with continuous DIFFUSION runs. Therefore, at the destine stage, an Eulerian path should be found for the logic function. Every discontinuity causes an increase in the area as well as a reduction in the clock rate and performance. The realization of a logic function using the static CMOS technology is done through different methods, most of which are based on the Uehara's method. In this paper, an algorithm is suggested that finds the Eulerian path and allows the implementation of the circuit with continuity in the DIFFUSION region that results in minimum area. In a case where there is no Eulerian path, the possible sub-paths are found. In addition, the algorithm gives information that helps the layout generation.

This paper provides an overview of the design of thread reinforced soil structures with a particular emphasis on the influence of the strength criterion. Due to the heterogeneity of the material a macroscopic strength criterion is determined and discussed for thread reinforced soil using the homogenization method for periodic medium in the yield design range. Various types of potential failure mechanisms are analyzed and pointed out by using the failure design theory which allows the stability analysis of a reinforced embankment. An account of the results are presented and compared with recent test results. Current evidence on the feasibility of this type of reinforcing is discussed along the variation of different parameters. Conclusion bears on general design and defines some considerations to be included in such analysis.      

Background: Prostate cancer is the third leading cause of death and is the most common cause of cancer in elderly men. Regarding to the low accuracy of screening methods such as prostate-specific antigen (PSA), Digital Rectal Examination (DRE) and trans rectal ultrasound (TRUS) in detection and localization of tumor, Magnetic Resonance Imaging (MRI) and DIFFUSION Weighted Imaging (DWI) attracted many attentions in the past years. DWI reveals micro-molecular DIFFUSION, which is the Brownian motion of the spins in biologic tissues. This technique can delineate pathologic lesions with high tissue contrast against generally suppressed background signal. In this paper, the value of DWI in detection of prostate cancer is studied.Methods: In this cross-sectional study, the studied population are suspicious patients to prostate cancer based on high Prostatic Specific Antigen level or abnormal Digital Rectal Examination who refered for prostate biopsy to radiology department of Hazrate- Rasoul Hospital during the year 2011. The results of DWI are compared to biopsy results for all patients.Results: Eighty five patients are selected. The DWI sensitivity in detecting of prostate cancer is 100%, specificity 97.1% and positive and negative predictive values are 89.5% and 100%, respectively. The results showed that if DWI reports the prostate cancer as negative, the result was highly reliable and if it reports as positive, although the report was not 100% reliable, but it still had high reliability, more than 90%.Conclusion: DWI had high accuracy in detecting prostate cancer for patients with cancer. Also the accuracy of this method for patients without prostate cancer was acceptable compared to the other common methods.

The control of cardiovascular disease, especially coronary artery disease, is regarded as one of the most important health problems in the worid. Nearly 25 percent of the worid total mortality rate is due to cardiovascular disease. So far many research studies have been carried out to control cardiovascular disease risk factors, that most of these studies have been quantitative studies not paying enough attention to deep comprehention and understanding of this phenomenon, while recognition and detection of the structure and nature of a phenomenon must be investigated using qualitative research methods. In this regard, this research was a qualitative study using Grounded theory model carried out to determine. The main structure of the control of coronary artery disease among the patients. The Data analysis of the result collected from the research participants (in eluding coronary patients, and their families, cardiologists and nurses) and creating concepts and variables such as transient care, lock of enough knowledge and understanding of the nature of the disease and lack or effective care relation resulted in the production of a Core variable named, "CONTINOUS care" which integrate the resulted concepts of the research data. This finding has been proposed as a new caring approch. This approach requiers four steps of orientation, sensitization, control and evaluation processes to control and reduce the complication of the disease, and to increase the quality of life of coronary patients.

Background: Multiple sclerosis (MS) is a chronic disease that begins most commonly in young adults and is characterized pathologically by multiple areas of central nervous system (CNS) white matter inflammation, demyelination, and glial scarring. The most valuable aid for diagnosis is magnetic resonance imaging (MRI). New type of MRI has been developed on the basis of molecular DIFFUSION which capable of detecting acute and active lesions. Early diagnosis and treatment is possible to stop or slowdown progression of disease. The aim of this study is to compare the findings of conventional and DIFFUSION- weighted (DW) MRI in detection cerebral lesions of MS.Methods: Thirty patients with clinically definite MS and 30 healthy volunteers were studied in a descriptive-prospective survey over a twelve-month period of time.Conventional and DW MRI were used in both groups. Total number, morphology, location and the mean size of the intra-cerebral plaques of MS were compared between group. The sensitivity and the specificity of both imaging methods in detecting these plaques were determined.Results: Thirty patients with MS with the mean age of 32.76±8.79 years and 30 healthy individuals with the mean age of 32.75±9.23 years were enrolled. Plaque within the brain was significantly higher by the conventional method (P<0.05). Ovoid lesions were greater in number in the conventional method group. More lesions were detected by the conventional method in the areas of periventricle, centrum semiovale and corpus callosum. Regarding the size of plaque, the minimum measurement was significantly lower in the conventional method group. The sensitivity of both methods was 100%. The specificity of conventional and DW MRI was 86.6% and 96.6%, respectively.Conclusion: In our study the sensitivity of both methods was the same but the specificity of DW MRI was higher. DW MRI may detect lesions which are not detectable by the routine methods.

Introduction The staging of endometrial carcinoma is now performed based on postoperative pathological assessments. If the staging of the cancer could be possible with a preoperative non-invasive method, based on the International Federation of Gynecology and Obstetrics system, a more appropriate treatment protocol can be recommended for patients. This study was performed aimed to evaluate the diagnostic value of dynamic magnetic resonance imaging with DIFFUSION-weighted imaging in the staging of endometrial carcinoma, based on the postoperative histopathological reference standard. Methods This prospective study was conducted in 2016-2021 on 35 patients with endometrial cancer referred to Ghaem Hospital in Mashhad. The staging of endometrial cancer was performed based on MRI findings and pathological samples. The diagnostic value of MRI was calculated to distinguish stages 1 from 2 and 1A from 1B. The lesion dimensions in the MRI and the pathological samples were compared using independent-sample t-test and the lesion dimensions between different stages using the ANOVA test by SPSS (version 17). P<0. 05 was considered statistically significant. Results According to the findings of MRI and pathology, the majority of patients (93. 3%) were in stage 1, and 2 (6. 7%) were in stage 2. The sensitivity, specificity, positive and negative predictive value in differentiating stage 1 from stage 2 was 100%, and the sensitivity, specificity, positive and negative predictive value of MRI in differentiating IA from IB was 100%. Conclusion It seems that dMRI by DWI method can be used in the staging of endometrial tumors in the initial stages (stage 1 from 2 and IA from IB) with diagnostic value.